| Augustana College | Private, For-profit, 4 years or more | Masters | Sioux Falls, 57197 |
| Avera McKennan Hospital School of Radiologic Technology | Private, For-profit, 2 to 4 years | Non-degree granting | Sioux Falls, 57117 |
| Colorado Technical University of Sioux Falls | Private, Non-profit, 4 years or more | Masters | Sioux Falls, 57108 |
| Kilian Community College | Private, For-profit, 2 to 4 years | Associates | Sioux Falls, 57103 |
| National American University-Sioux Falls | Private, Non-profit, 4 years or more | Bachelors | Sioux Falls, 57105 |
| North American Baptist Seminary | Private, For-profit, 4 years or more | Doctoral and First Professional | Sioux Falls, 57105 |
| Sioux Valley Hospital-School of Radiologic Technology | Private, For-profit, 2 to 4 years | Non-degree granting | Sioux Falls, 57117 |
| Southeast Technical Institute | Public, 2 to 4 years | Associates | Sioux Falls, 57107 |
| Stewart School | Private, Non-profit, 2 to 4 years | Non-degree granting | Sioux Falls, 57104 |
| University of Sioux Falls | Private, For-profit, 4 years or more | Masters | Sioux Falls, 57105 |
